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This work comments on an article published in the recent issue of the . Rhabdomyolysis is a complex condition with symptoms such as myalgia, changes to urination, and weakness. With the potential for substantial kidney impairment, it has also been shown to be a severe complication of coronavirus disease 2019 (COVID-19).

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Article Synopsis
  • - Hypokalemia is a common issue typically seen as mild with no symptoms, but moderate-to-severe cases can lead to serious health problems.
  • - Severe hypokalemia (potassium level of 2.5 mEq/L or lower) can cause symptoms like muscle cramps, weakness, and severe complications, including renal and respiratory failure.
  • - The text presents a case of a patient with extremely low potassium levels (1.4 mEq/L) due to furosemide use, who only reports muscle spasms despite the severity of their condition.
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Carnitine palmitoyltransferase II (CPT2) deficiency is a rare inherited disorder affecting fatty acid metabolism. This enzymatic defect presents with a broad clinical spectrum, from severe neonatal forms that can be fatal, to milder myopathic variants characterized by myalgia and recurrent myoglobinuria in adolescence and adulthood. Herein, we report the case of a male patient who developed exertional rhabdomyolysis and acute kidney injury due to CPT2 deficiency.

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Article Synopsis
  • * The patient, with a history of chronic kidney disease and on various medications, initially arrived at the hospital after experiencing difficulties walking and swelling.
  • * Treatment involved intravenous fluids and albumin, resulting in improved kidney function, highlighting the importance of monitoring CK levels in asymptomatic COVID-19 patients, especially those with certain risk factors.
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