A theory for the mechanism of electrical bone stimulation proposes that passage of an electric current reduces the local PO2 and raises the pH near the cathode, thereby creating a favorable environment for osteogenesis. To study the effects of electric current passage on the PO2, PCO2 and pH in the vicinity of the electrodes in vivo, a wire electrode spiralled around the catheter of a clinical mass spectrometer was placed in dog muscle. Electrodes were made of stainless steel or platinum. With a cathode located in the tissue, a 20-microA direct constant current caused a drop in PO2 of 5-10 mmHg and a drop in PCO2 of 2-6 mmHg, both reaching plateaus again within five to 20 minutes. The time required to reach this new equilibrium was shorter for platinum than for stainless steel. When the electric current was turned off, PO2 and PCO2 reversed to their original values. Because of the high buffer capacity of tissue, it is highly unlikely that 20-microA current would induce a change in pH.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Three-Dimensional Electrical Impedance Imaging During Spontaneous Breathing Trials in Patients With Acute Hypoxic Respiratory Failure: A Pilot Study.
Crit Care Explor
January 2025
Department of Mathematics and School of Biomedical Engineering, Colorado State University, Fort Collins, CO.
The purpose of this work is to evaluate the feasibility of lung imaging using 3D electrical impedance tomography (EIT) during spontaneous breathing trials (SBTs) in patients with acute hypoxic respiratory failure. EIT is a noninvasive, nonionizing, real-time functional imaging technique, suitable for bedside monitoring in critically ill patients. EIT data were collected in 24 mechanically ventilated patients immediately preceding and during a SBT on two rows of 16 electrodes using a simultaneous multicurrent source EIT system for 3D imaging.
View Article and Find Full Text PDFMolecular Photoelectrocatalysis for Radical Reactions.
Acc Chem Res
January 2025
State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, and Discipline of Intelligent Instrument and Equipment, Xiamen University, Xiamen 361005, P. R. China.
ConspectusMolecular photoelectrocatalysis, which combines the merits of photocatalysis and organic electrosynthesis, including their green attributes and capacity to offer novel reactivity and selectivity, represents an emerging field in organic chemistry that addresses the growing demands for environmental sustainability and synthetic efficiency. This synergistic approach permits access to a wider range of redox potentials, facilitates redox transformations under gentler electrode potentials, and decreases the use of external harsh redox reagents. Despite these potential advantages, this area did not receive significant attention until 2019, when we and others reported the first examples of modern molecular photoelectrocatalysis.
View Article and Find Full Text PDFA cross-sectional study characterizing the prevalence of utility service outages across demographic characteristics and health correlates in New York City.
Environ Epidemiol
February 2025
Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Background: Utility services for electricity, gas, heat, and hot water are necessities for everyday activities (e.g., lighting, cooking, and thermal safety).
View Article and Find Full Text PDFHigh-throughput evaluation of half-metallicity of CoMnSi Heusler alloys using composition-spread films and spin-integrated hard X-ray photoelectron spectroscopy.
Sci Technol Adv Mater
January 2025
Magnetic Functional Device Group, Research Center for Magnetic and Spintronic Materials (CMSM), National Institute for Materials Science (NIMS), Tsukuba, Japan.
We demonstrate high-throughput evaluation of the half-metallicity of CoMnSi Heusler alloys by spin-integrated hard X-ray photoelectron spectroscopy (HAXPES) of composition-spread films performed with high-brilliance synchrotron radiation at NanoTerasu, which identifies the optimum composition showing the best half-metallicity. Co Mn Si composition-spread thin films for = 10-40% with a thickness of 30 nm are fabricated on MgO(100) substrates using combinatorial sputtering technique. The 2-ordering and (001)-oriented epitaxial growth of CoMnSi are confirmed by X-ray diffraction for = 18-40%.
View Article and Find Full Text PDFEnhancing road safety of PLEVs by novel vehicle concepts: A comprehensive investigation on regulations, accident statistics, and perception of riders in Europe.
Heliyon
January 2025
Department of Industrial Engineering, Università degli Studi di Firenze, Via di Santa Marta, 3, 50139, Firenze, Italy.
The rise of Personal Light Electric Vehicles (PLEVs), including electric bicycles and electric kick scooters, represents a relevant trend in current urban mobility. PLEVs offer economic, social, and environmental advantages, making them increasingly attractive for short-distance travel. Despite their benefits, concerns about the safety of PLEVs, particularly related to road accidents, have arisen due to their growing presence in urban areas.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!