Five patients were bitten by the Malayan krait Bungarus candidus (Linnaeus) in eastern Thailand or north western Malaya. Two patients were not envenomed but the other three developed generalised paralysis which progressed to respiratory paralysis in two cases, one of which ended fatally. One patient showed parasympathetic abnormalities. Anticholinesterase produced a dramatic improvement in one patient. Another patient probably benefited from paraspecific antivenom. The efficacy of antivenoms and adjuvants such as anticholinesterases in patients with neurotoxic envenoming requires further study.
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http://dx.doi.org/10.1136/bmj.286.6366.678 | DOI Listing |
Trans R Soc Trop Med Hyg
January 2025
Toxic Organisms Research Centre, Faculty of Science, University of Khartoum, Sudan.
Snakebite envenomation (SBE) is a neglected tropical disease. It causes substantial morbidity and mortality in Sudan. Despite its endemicity, there is a substantial lack of up-to-date data on venomous snakes and their geographical distribution in Sudan, with most information dating back to the early twentieth century.
View Article and Find Full Text PDFTrans R Soc Trop Med Hyg
January 2025
School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8102, Japan.
Background: Little is known about snakebites by Naja samarensis, a species unique to the Philippines. The aim here is to describe the clinical and epidemiological characteristics of patients bitten by this medically important cobra in the Eastern Visayas.
Methods: A hospital-based prospective study analysed the features of snakebite patients attending Eastern Visayas Medical Center between June 2022 and May 2023.
Trans R Soc Trop Med Hyg
January 2025
Department of Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal.
Background: Snakebite envenomation is a global public health concern, especially in tropical and subtropical regions. We describe the demography, presentations, treatments and outcomes of snakebites from a community snakebite treatment centre in Nepal.
Methods: This was a retrospective study of snakebite cases from 2008 to 2021 presenting in a community-based treatment centre in eastern Nepal.
Toxins (Basel)
December 2024
School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam 690 525, Kerala, India.
The intricate combination of organic and inorganic compounds found in snake venom includes proteins, peptides, lipids, carbohydrates, nucleotides, and metal ions. These components work together to immobilise and consume prey through processes such as paralysis and hypotension. Proteins, both enzymatic and non-enzymatic, form the primary components of the venom.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
December 2024
Animal Physiology Unit, Department of Zoology, University of Ibadan, Ibadan, Nigeria.
Naja haje envenoming manifests organ system disorders leading to severe fatalities due to the venom's toxins. The neutralizing capacity of kaempferol has been reported against some medically significant snake venoms with exception of N. haje venom (NhV).
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