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DNA activates human polymorphonuclear leukocytes--a new importance of DNA presented in the inflammatory tracheobronchial secretion.
Arch Immunol Ther Exp (Warsz)
September 1991
Department of Pneumonology and Allergology, Medical Academy, Lódź.
DNA from calf thymus (1 to 10 micrograms/ml) was shown to stimulate the release of myeloperoxidase (MPO) and low amounts of H2O2 (about 1.5 nmoles/10(6) cells) from human polymorphonuclear leukocytes (PMNL). PMNL during 60 min incubation with DNA (10 micrograms/ml) and with DNA and cytochalasin B (4.
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