CC (B4/B4) chickens exhibited prolonged skin graft survival when pretreated by injections of whole blood from CB.R1 (B12.r1/B12.r1) donors. The difference in survival time was statistically significant between grafts from CB.R1 donors and from CB donors, differing only at the B-G region product. Pretreatment with CB blood (B12/B12) had no effect on graft survival. The results indicate that B-G region of the MHC has an effect on histocompatibility in the chicken system used.
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