The Boston group have devoted 10 years to a thoughtful, comprehensive, and much needed study that will undoubtedly become a classic reference in the field. If the emphasis is placed on differences that reached statistical significance, the major finding is minimal outcome differences between exploratory, insight-oriented (EIO) and reality-adaptive, supportive (RAS) therapies with, if anything, significant advantages to RAS in recidivism and performance. Selective beneficial effects for EIO gain only very weak support. The results should contribute to a climate wherein we may move on to study how psychotherapy and pharmacotherapy can be combined to achieve optimal results and minimize toxic effects.
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http://dx.doi.org/10.1093/schbul/10.4.604 | DOI Listing |
Sensors (Basel)
January 2025
Seamless Trans-X Lab (STL), School of Integrated Technology, Yonsei University, Incheon 21983, Republic of Korea.
In the domain of autonomous driving, trajectory prediction plays a pivotal role in ensuring the safety and reliability of autonomous systems, especially when navigating complex environments. Unfortunately, trajectory prediction suffers from uncertainty problems due to the randomness inherent in the driving environment, but uncertainty quantification in trajectory prediction is not widely addressed, and most studies rely on deep ensembles methods. This study presents a novel uncertainty-aware multimodal trajectory prediction (UAMTP) model that quantifies aleatoric and epistemic uncertainties through a single forward inference.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Institute of Robotics, Autonomous System and Sensing, School of Electronic and Electrical Engineering, University of Leeds, Leeds LS2 9JT, UK.
Knee joint disorders pose a significant and growing challenge to global healthcare systems. Recent advancements in robotics, sensing technologies, and artificial intelligence have driven the development of robot-assisted therapies, reducing the physical burden on therapists and improving rehabilitation outcomes. This study presents a novel knee exoskeleton designed for safe and adaptive rehabilitation, specifically targeting bed-bound stroke patients to enable early intervention.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Helmholtz Institute Ulm (HIU), Helmholtzstraße 11, 89081 Ulm, Germany.
Potassium-ion batteries (KIBs) have attracted significant attention in recent years as a result of the urgent necessity to develop sustainable, low-cost batteries based on non-critical raw materials that are competitive with market-available lithium-ion batteries. KIBs are excellent candidates, as they offer the possibility of providing high power and energy densities due to their faster K diffusion and very close reduction potential compared with Li/Li. However, research on KIBs is still in its infancy, and hence, more investigation is required both at the materials level and at the device level.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Freiburg University Medical Center, 79106 Freiburg, Germany.
Given the poor prognosis of metastatic pancreatic adenocarcinoma (mPDAC), closer disease monitoring through liquid biopsy, most frequently based on serial measurements of cell-free mutated ( cfDNA), has become a highly active research focus, aimed at improving patients' long-term outcomes. However, most of the available data show only a limited predictive and prognostic value of single-parameter-based methods. We hypothesized that a combined longitudinal analysis of cfDNA and novel protein biomarkers could improve risk stratification and molecular monitoring of patients with mPDAC.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Electronic Engineering, Faculty of Applied Energy System, Jeju National University (JNU), Jeju City 63243, Republic of Korea.
We have executed a cost-effective approach to produce a high-performance multifunctional human-machine interface (HMI) humidity sensor. The designed sensors were ecofriendly, flexible, and highly sensitive to variability in relative humidity (%RH) in the surroundings. In this study, we have introduced a humidity sensor by using carbon paper (as both a substrate and sensing material) and a silver (Ag) conductive ink pen.
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