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Leptospirosis Causing Severe Acute Kidney Injury, Hyperbilirubinemia, and Thrombocytopenia: A Case Report.
Cureus
November 2024
Internal Medicine, Corewell Health, Royal Oak, USA.
Leptospirosis, an infection caused by the spirochete Leptospira and commonly attributed to the underdeveloped world, is frequently under-diagnosed in the United States. This report discusses the case of a 79-year-old male with no significant medical history who presented to the ED with recurrent falls. Initial laboratory results demonstrated severe acute kidney injury, hyperbilirubinemia, and thrombocytopenia.
View Article and Find Full Text PDFA Rare Case of Weil's Disease Presenting With Severe Hyperbilirubinemia and Acute Kidney Injury: A Diagnostic Challenge in Urban England.
Cureus
November 2024
Internal Medicine, Northumbria Healthcare NHS Trust, Newcastle-Upon-Tyne, GBR.
We present a rare and challenging case of Weil's disease in a patient who was admitted to the Critical Care Unit with a clinical suspicion of the condition. The patient showed a prompt response to treatment before laboratory confirmation was obtained. Leptospirosis, a zoonotic disease, is most commonly found in tropical and temperate regions.
View Article and Find Full Text PDFAtypical Cases of Leptospirosis: Insights From Georgia.
Case Rep Infect Dis
November 2024
Department of Infectious Diseases, Tbilisi State Medical University, Tbilisi, Georgia.
Pathogenic species are the source of leptospirosis, a common zoonotic infection that can cause a wide range of clinical manifestations, from minor flu-like symptoms to severe multiorgan failure. We present two peculiar cases of leptospirosis; they highlight the need for clinical awareness to improve patient outcomes and further knowledge of leptospirosis epidemiology and therapy by illuminating the difficulties in diagnosis and treatment. The first case involved a 30-year-old male presented with jaundice.
View Article and Find Full Text PDFAtypical clinical debut associated with Jarisch Herxheimer reaction in an asplenic patient with leptospirosis: case report and review.
BMC Infect Dis
November 2024
Internal Medicine resident, Fundacion Universitaria Juan N Corpas, Fundación Clínica Shaio, Dg. 115a #70c - 75, Bogotá, Colombia.
Background: Leptospirosis poses a diagnostic challenge owing to its wide array of symptoms, ranging from asymptomatic cases and febrile syndromes to severe disease with a high mortality rate. Risk factors are associated with exposure and the immune response, particularly in immunosuppressed patients.
Case Presentation: A clinical case involving a 49-year-old patient with a history of splenectomy and no immunization schedule.
Molecular and serological detection of acute canine leptospirosis and associated predictive risk factors in and around Chennai, India.
Microb Pathog
January 2025
Zoonoses Research Laboratory, Center for Animal Health Studies, Tamil Nadu Veterinary and Animal Sciences University, Chennai, 600 051, India.
Article Synopsis
- Leptospirosis, a re-emerging disease affecting both humans and dogs, was diagnosed in a study of 210 suspected dogs using MAT and PCR tests.
- The study found that 58.57% of the dogs had anti-leptospiral antibodies, with 23.33% confirmed as acutely infected, primarily influenced by factors like age, seasonal weather, outdoor exposure, and contact with rodents or wet environments.
- The identification of Leptospira interrogans in infected dogs highlights the importance of recognizing these risk factors for timely treatment and recovery strategies in canines.
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