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- The study investigates how β-tricalcium phosphate affects bone healing in rabbit mandibles after a defect is created.
- The research involved adult male rabbits, comparing a control group with a natural healing process against an experimental group treated with β-tricalcium phosphate over an 84-day period.
- Results showed significant regenerative changes in the experimental group, leading to an increase in bone tissue volume that ultimately matched the control group by the end of the study.
Glycerol Modulated Collagen Fibril Evolution and Lamellar Organization for Biomimetic Corneal Substitutes Construction.
Small
December 2024
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, Sichuan, 610065, China.
Collagen as the main structural component of the cornea exhibits unique and highly organized fibril lamellae, which contribute to the maintenance of corneal structure and transparency. Nevertheless, collagen assembly in vitro to create ideal artificial corneal substitutes with human cornea comparable thickness and optics is still limited. Here, glycerol as a regulator can reconcile collagen thickness, transparency, and permeability, a conflicting goal by current keratoprosthesis strategies.
View Article and Find Full Text PDFComparison of rose bengal-green light scleral crosslinking in rabbit eyes using different infiltration protocols - An Ex Vivo study.
Exp Eye Res
January 2025
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, NHC Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. Electronic address:
Different concentrations and infiltration times of rose bengal (Rb) were assessed for their impact on penetration depth and crosslinking efficacy in rabbit sclera. Fresh rabbit eyes were used. Rb solution with concentrations of 0.
View Article and Find Full Text PDFSubcutaneous BNP Injections in Rabbits: A Novel Approach to Mitigate Myocardial Remodeling in Atrial Fibrillation.
Discov Med
November 2024
Department of Cardiology, The People's Hospital of Liaoning Province, 110016 Shenyang, Liaoning, China.
Background: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with increased morbidity and mortality, highlighting the need for novel therapeutic strategies. This study aimed to evaluate the effects of B-type natriuretic peptide (BNP) on cardiac structural remodeling in a rabbit model of AF.
Methods: Rabbits were subjected to rapid pacing to induce an AF model, and BNP was delivered subcutaneously at a dose of 20 μg/kg/d twice per day for three weeks.
Cartilage Laser Engraving for Fast-Track Tissue Engineering of Auricular Grafts.
Int J Mol Sci
October 2024
National Medical Research Radiological Center, Koroleva St. 4, 249036 Obninsk, Russia.
In this study, the optimal engraving parameters were determined through the analysis of scanning electron microscopy (SEM) data, as follows: a laser power density of 5.5 × 10 W/cm, an irradiation rate of 0.1 mm/s, a well radius of 60 μm, a distance between well centers of 200 μm, and a number of passes for each well of 20.
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