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First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f.
BMC Res Notes
January 2025
Bioinformatics Center, North-Eastern Hill University, Shillong, 793022, India.
Objectives: Nepenthes, sometimes known as tropical pitcher plants or monkey cups, is a carnivorous plant genus that contains more than 160 species. Nepenthes khasiana, India's sole representative of the genus, is a rare and endangered dioecious plant endemic to North-east India. Despite the fact that it is a prominent insectivorous plant in the Nepenthaceae family, genomic resources for the species are limited, making genomic breeding and understanding the genetic basis of botanical carnivory difficult.
View Article and Find Full Text PDFLewy body diseases and the gut.
Mol Neurodegener
January 2025
Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.
Gastrointestinal (GI) involvement in Lewy body diseases (LBDs) has been observed since the initial descriptions of patients by James Parkinson. Recent experimental and human observational studies raise the possibility that pathogenic alpha-synuclein (⍺-syn) might develop in the GI tract and subsequently spread to susceptible brain regions. The cellular and mechanistic origins of ⍺-syn propagation in disease are under intense investigation.
View Article and Find Full Text PDFRestoring riparian habitats for benefits to biodiversity and human livelihoods: a systematic map protocol for riparian restoration approaches in the tropics.
Environ Evid
January 2025
Modelling, Evidence and Policy RG, SNES, Newcastle University, Newcastle, NE1 7RU, UK.
Background: Riparian zones are vital transitional habitats that bridge the gap between terrestrial and aquatic ecosystems. They support elevated levels of biodiversity and provide an array of important regulatory and provisioning ecosystem services, of which, many are fundamentally important to human well-being, such as the maintenance of water quality and the mitigation of flood risk along waterways. Increasing anthropogenic pressures resulting from agricultural intensification, industry development and the expansion of infrastructure in tropical regions have led to the widespread degradation of riparian habitats resulting in biodiversity loss and decreased resilience to flooding and erosion.
View Article and Find Full Text PDFMulti-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis.
J Transl Med
January 2025
Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Background: Psoriasis is a common chronic, recurrent, immune-mediated disease involved in the skin or joints or both. However, deeper insight into the genetic susceptibility of psoriasis is still unclear.
Methods: Here we performed the largest multi-ancestry meta-analysis of genome-wide association study including 28,869 psoriasis cases and 443,950 healthy controls.
Probiotic active gel promotes diabetic wound healing through continuous local glucose consumption and antioxidant.
J Nanobiotechnology
January 2025
Shandong Key Laboratory of Proteins and Peptides Pharmaceutical Engineering, Shandong Universities Key Laboratory of Biological Medicine, School of Life Science and Technology, Shandong Second Medical University, 7166 # Baotong West Street, Weifang, Shandong, 261053, People's Republic of China.
Background: Diabetic foot ulcers (DFU) are severe complications of diabetes, posing significant health and societal challenges. Accumulation of reactive oxygen species (ROS) and elevated glucose levels are primary factors affecting diabetic wound healing. Achieving effective treatment by reducing ROS alone is challenging, as high glucose levels continuously drive ROS production.
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