Newly synthesized DNA is undermethylated in E. coli K-12. The amount of N6-methyl deoxyadenylic acid in labeled DNA varied from 0.3 mol% of total adenine for a 2-min pulse to 1.7 mol% for DNA that was labeled for more than two generations.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC215653 | PMC |
http://dx.doi.org/10.1128/jb.159.1.421-423.1984 | DOI Listing |
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