A 45-year-old man with an internal carotid artery occlusion, cerebral hemispheric infarction, and an ipsilateral central retinal artery occlusion developed anterior segment necrosis after retrobulbar injection of lidocaine hydrochloride (Xylocaine) for treatment of an occlusion of the central retinal artery. Multiple embolic plaques in the retinal circulation with occlusion of the posterior ciliary arteries were found. The clinical and postmortem histopathologic findings are presented.

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