Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0016-5107(84)72342-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Roles of alpha-7 nicotinic acetylcholine receptors and spleen in the lung injury induced by a repeated saline lavage in rat.
BMC Pulm Med
September 2022
Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: The study aimed to determine whether or notα7 nicotinic acetylcholine receptors (α7nAChR) induce anti-inflammatory effects directly in the lung or through the spleen pathway in a sterile model of lung injury by saline lavage.
Methods: Male Sprague Dawley rats were divided into seven groups; Sham, splenectomy (SPX), saline lavage (LAV), LAV treated with α7nAChR agonist nicotine (LAV + NIC), and LAV treated with NIC and a selective α7nAChR antagonist MLA (LAV+MLA+NIC), LAV and splenectomy (LAV+SPX), and LAV+SPX treated with nicotine (LAV+SPX+NIC). Tracheostomy and catheterization of the femoral artery were performed under deep anesthesia.
Hepatic effects of an open lung strategy and cardiac output restoration in an experimental lung injury.
Acta Anaesthesiol Scand
May 2010
Department of Anaesthesia and Critical Care, University of Würzburg, Oberdürrbacherstrasse 6, 97080 Würzburg, Germany.
Background: Ventilation with high positive end-expiratory pressure (PEEP) can lead to liver dysfunction. We hypothesized that an open lung concept (OLC) using high PEEP impairs liver function and integrity dependent on the stabilization of cardiac output.
Methods: Juvenile female Pietrain pigs instrumented with flow probes around the common hepatic artery and portal vein, pulmonary and hepatic vein catheters underwent a lavage-induced lung injury.
Gas exchange and lung inflammation using nasal intermittent positive-pressure ventilation versus synchronized intermittent mandatory ventilation in piglets with saline lavage-induced lung injury: an observational study.
Crit Care Med
January 2008
Department of Pediatrics, Division of Neonatology, University of Minnesota Medical School, Minneapolis, MN, USA.
Objective: Physiologic and pathologic comparison of two modes of assisted ventilation, nasal intermittent positive-pressure ventilation (NIPPV) and synchronized intermittent mandatory ventilation (SIMV), in spontaneously breathing term newborn piglets with saline lavage-induced lung injury.
Design: After inducing acute lung injury via repetitive saline lavage, piglets were randomized to NIPPV (n = 12) or SIMV (n = 11) and treated for 6 hrs.
Setting: Clinical laboratory.
High frequency oscillatory ventilation and prone positioning in a porcine model of lavage-induced acute lung injury.
BMC Anesthesiol
April 2006
Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Würzburg, Oberdürrbacher Str, 6, 97080 Würzburg, Germany.
Background: This animal study was conducted to assess the combined effects of high frequency oscillatory ventilation (HFOV) and prone positioning on pulmonary gas exchange and hemodynamics.
Methods: Saline lung lavage was performed in 14 healthy pigs (54 +/- 3.1 kg, mean +/- SD) until the arterial oxygen partial pressure (PaO2) decreased to 55 +/- 7 mmHg.
Slow moderate pressure recruitment maneuver minimizes negative circulatory and lung mechanic side effects: evaluation of recruitment maneuvers using electric impedance tomography.
Intensive Care Med
December 2005
Department of Anesthesia and Intensive Care, Sahlgrenska University Hospital, 41345, Gothenburg, Sweden.
Objective: To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography.
Design And Setting: Experimental study in animal model of acute lung injury in an animal research laboratory.
Subjects: Fourteen pigs with saline lavage induced lung injury.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!