Conventional microsurgical reanastomosis was compared with laser microsurgical reanastomosis of previously ligated uterine tubes in 14 rabbits. A final laparotomy was performed to determine adhesion formation and uterine tube patency, and a histologic examination was done of the anastomosis sites using four histologic indices for grading. Laser microsurgery produced significantly less adhesions (mean +/- standard error of the mean adhesion score, 0.79 +/- 0.24) than conventional microsurgery (2.29 +/- 0.13, P less than 0.001). However, there was no significant difference in all four histologic indices of tissue reunion at the anastomosis site between the two types of surgical technique. In a separate experiment, CO2 laser was found to be unable to weld uterine tubes successfully. Thus, the CO2 laser can significantly reduce postoperative adhesions in microsurgical uterine tube reanastomosis but without any significant histologic difference in tissue reunion, compared with conventional microsurgery.
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Lasers Surg Med
January 2025
Wyant College of Optical Science, University of Arizona, Tucson, Arizona, USA.
Study Objective: We present the results of the first feasibility and safety study of a novel multi-modality falloposcope, in 19 volunteers. The falloposcope incorporated multispectral fluorescence imaging (MFI) and optical coherence tomography (OCT) for evaluation of the fallopian tubes (FT).
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View Article and Find Full Text PDFPharmaceuticals (Basel)
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School of Health Sciences, Cappadocia University, Nevsehir 50400, Turkey.
: Cyclophosphamide (CP) is widely used for treating various cancers and autoimmune diseases, but it causes damage to reproductive organs due to oxidative stress (OS) and inflammation. Boric acid (BA) has antioxidant properties that may help reduce OS, which is critical for preserving uterine functionality, particularly for cancer patients considering pregnancy after cryopreservation. This study aimed to determine whether BA could diminish CP-induced toxicity in the uterus and fallopian tubes (FT) using CP-induced toxicity in a rat model.
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Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
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View Article and Find Full Text PDFAfr J Reprod Health
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