The minimal inhibitory and bactericidal concentration of 18 antibiotics for 412 isolates of group B streptococci from newborns, mothers or pregnant women were determined. 3.2% of these strains were less susceptible to penicillin G, 1% failed to be inhibited by erythromycin and 1% by chloramphenicol. Antibiotic-killing kinetics was studied with beta-lactams, aminoglycosides, and in combination for 20 isolates. Killing was accelerated by the combination. For these reasons, at least at the beginning of the treatment, the association of ampicillin and an aminoglycoside can be recommended.
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