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Studies on 1432 thyrotoxicosis cases attracted the attention to a relatively high incidence (7.7%) of its association with damage to the central nervous system. 27 of 110 patients with combined type of thyrotoxicosis developed malignant exophthalmos. On the grounds of the studies of long-term results of the surgical treatment of these cases one could come to the conclusion, that surgical treatment of combined types of thyrotoxicosis was an efficient method. The clinic recommends complex preoperative management and a postoperative care procedure.

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