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Larvicidal activity of methanolic and aqueous extracts of Lavandula dentata and Nerium oleander flowers against the vector of avian malaria Culiseta longiareolata.
Trop Biomed
December 2024
Farhat Abbes University, Department of Biochemistry, Biochemistry Laboratory, Setif, Algeria.
In light of the adverse effects of chemical insecticides on the environment and human health, as well as the development of mosquito resistance to them, this study explores the potential of methanol and aqueous flower extracts from Lavandula dentata and Nerium oleander as bioinsecticides against Culiseta longiareolata mosquitoes. Additionally, it aims to assess the impact of these extracts on enzymatic biomarkers and biochemical composition of fourth instar larvae of Culiseta longiareolata.Qualitative analysis revealed the presence of flavonoids, terpenes, gallic and catechic tannins in both plant extracts.
View Article and Find Full Text PDFCardiotoxicity Associated With a Low Doses of 5-FU Promotes Morphoquantitative Changes in the Intrinsic Cardiac Nervous System.
Cardiovasc Toxicol
January 2025
Department of Morphological Sciences, State University of Maringa, Maringa, Parana, Brazil.
5-Fluorouracil (5-FU) is a chemotherapeutic that is used to treat solid tumors. However, 5-FU is associated with several side effects, including cardiotoxicity. Considering the importance of the intrinsic cardiac nervous system (ICNS) for the heart and that little is known about effects of 5-FU on this nervous system plexus, the purpose of the present study was to evaluate effects 5-FU at a low dose on the ICNS and oxidative and inflammatory effects in the heart in Wistar rats.
View Article and Find Full Text PDFTurmeric counteracts manganese-associated deteriorations in liver and kidney tissues: histomorphometric and biochemical insights.
J Mol Histol
December 2024
Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Nowadays, Manganese (Mn) become an unavoidable ingredient in agriculture, medical and manufacturing industries. Manganese deficiency is rare, and even though recurrent exposure to manganese is inevitable for humans, concerns have been voiced regarding public health hazards. This research was designed to evaluate the manganese toxicity and potential protective effects of turmeric in Swiss albino male mice.
View Article and Find Full Text PDFPathological Alterations in Heart Mitochondria in a Rat Model of Isoprenaline-Induced Myocardial Injury and Their Correction with Water-Soluble Taxifolin.
Int J Mol Sci
October 2024
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, 142290 Pushchino, Russia.
Mitochondrial damage and associated oxidative stress are considered to be major contributory factors in cardiac pathology. One of the most potent naturally occurring antioxidants is taxifolin, especially in its water-soluble form. Herein, the effect of a 14-day course of the peroral application of the water-soluble taxifolin (aqTAX, 15 mg/kg of body weight) on the progression of ultrastructural and functional disorders in mitochondria and the heart's electrical activity in a rat model of myocardial injury induced with isoprenaline (ISO, 150 mg/kg/day for two consecutive days, ) was studied.
View Article and Find Full Text PDFEffects of bulk forms and nanoparticles of zinc and copper oxides on the abundance, nitrogen cycling and enzymatic activities of microbial communities, morphometric parameters and antioxidant status of Hordeum vulgare L.
Environ Geochem Health
November 2024
Southern Federal University, Rostov-On-Don, 344090, Russian Federation.
Uncontrolled use or improper disposal of bulk forms and nanoparticles of heavy metals may lead to their release into the environment. Coastal and floodplain ecosystems are particularly vulnerable, and the effects of metal nanoparticles on Fluvisol and Stagnic Fluvisol are poorly studied. This study aims to examine the effect of heavy metals on the enzymatic activity of the soil, the abundance of culturable microorganisms, growth, and antioxidant status of H.
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