[Test-systems for biomonitoring based on membrane-bound enzyme complexes. III. An assessment of the genotoxic action of industrial effluents in the Ames test-system with metabolic activation by microsomal monooxygenases].

Using the Ames mutation test system II samples of the Baikal pulp and paper effluents selected at different dates have been investigated. In 9 cases the effluent samples possessed no mutagenic activity; some samples revealed frame shift mutations, i.e. a medium mutagenic effect. In the presence of a metabolic activation system from the livers of phenobarbital-induced rats the mutagenic activity was considerably reduced.