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FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment.
J Mol Endocrinol
February 2021
Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Tokushima, Japan.
FGF23 is a phosphaturic hormone produced by bone. FGF23 reduces serum phosphate by suppressing proximal tubular phosphate reabsorption and intestinal phosphate absorption. After the identification of FGF23, several kinds of hypophosphatemic rickets/osteomalacia such as X-linked hypophosphatemia (XLH) and tumor-induced osteomalacia (TIO) have been shown to be caused by excessive actions of FGF23.
View Article and Find Full Text PDF[The clinical diagnostic significance of auto antibodies to CD74 at axial spondylarthritis.].
Klin Lab Diagn
July 2019
The Federal State Budget Educational Institution "The V.A. Almazov Federal Medical Research Center" of Minzdrav of Russia, 197341, St. Petersburg, Russia.
The modern diagnostic approaches permit to diagnose axial spondylarthrosis (axSpA) at roentgenologic stage corresponding to ankylosing spondylitis (AS). While early diagnostic of non-roentgenologic axSpA (nr-axSpA) is still complicated. This situation conditions a need in searching new laboratory biomarkers for early diagnostic of spondylarthrosis, including auto-antibodies to antigen CD74 described recently.
View Article and Find Full Text PDFOperative treatment of corrosive esophageal strictures.
Wiad Lek
August 2018
Department Of Surgery, Medical Faculty No 2, National Pirogov Memorial Medical University, Vinnytsya, Ukraine.
Objective: Introduction: Nowadays operative treatment of corrosive esophageal strictures remains one of the difficult and unsolved problems in surgery. The level of postoperative complications such as anastomotic leak (develops in 7-30% of cases), infections, pneumonia, pleural empyema, mediastinitis, peritonitis, postoperative corrosive strictures is still rather high. The aim of our work was to improve the results of surgical treatment of patients with corrosive esophageal strictures by analyzing and refining on conservative therapy options as well as differentiated approach to each operative treatment method.
View Article and Find Full Text PDF[IgG4-related sclerosing disease of the larynx].
Vestn Otorinolaringol
July 2017
M.F. Vladimirov Moscow Regional Research Clinical Institute, Moscow, Rusia, 129110.
IgG4-related sclerosing disease of the larynx (IgG4-SD) is a recently described immunodependent systemic pathology characterized by diffusive or focal inflammatory infiltration of the affected organs and tissues by plasma cells expressing IgG4; it is accompanied by the subsequent development of obliterative phlebitis and fibrosclerosis associated with the increase of the serum IgG4 level. According to the recently published materials, the disease can also develop in the respiratory system. The present article describes the first documented case of IgG4-related sclerosing disease with the isolated lesion of the larynx.
View Article and Find Full Text PDFDifferentiated tactics of diagnostic videothoracoscopy (VTHS) in a pleural exudate syndrome, which ought to be treated with hydrothorax elimination and artificial pneumothorax creation, was proposed. Further roentgenological investigation permits to create a plan for the operation conduction and a certain anesthesia application. Criteria for the operation planning and the anesthesiological support choice were elaborated.
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