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[Celebrating the 80th Anniversary of the Japanese Journal of Radiological Technology: A Reflection on the Future of the JSRT].
Nihon Hoshasen Gijutsu Gakkai Zasshi
January 2025
Department of Molecular Imaging, Clinical Collaboration Unit, School of Medical Sciences, Fujita Health University.
Reflections on World War II and the Holocaust on the 80th anniversary of their conclusion.
Clin Dermatol
October 2024
Jefferson Center for International Dermatology and Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Complement Factor H Is an ICOS Ligand Modulating Tregs in the Glioma Microenvironment.
Cancer Immunol Res
January 2025
Section of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden.
Article Synopsis
- * This study found that complement factor H (FH) acts as an ICOS ligand, enhancing Treg survival and function while increasing TGF-beta and IL-10 secretion, which suppresses T-cell activity.
- * Analysis in mouse models and patient data revealed that higher FH levels are linked to more Tregs and poorer patient outcomes, indicating that targeting FH could improve glioma treatment and prognosis.
Clinical metabolomics: current state and prospects in Russia.
Biomed Khim
September 2024
Institute of Biomedical Chemistry, Moscow, Russia.
Using analytical technologies it is possible now to measure the entire diversity of molecules even in a small amount of biological samples. Metabolomic technologies simultaneously analyze thousands of low-molecular substances in a single drop of blood. Such analytical performance opens new possibilities for clinical laboratory diagnostics, still relying on the measurement of only a limited number of clinically significant substances.
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