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Rheumatoid Arthritis and Pericardial Effusion - A Unique Major Manifestation.
Eur J Case Rep Intern Med
January 2024
Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal.
Introduction: Pericardial effusion is common in the setting of rheumatoid arthritis (RA); however, it is rarely its first manifestation.
Case Description: An 82-year-old male presented with abdominal pain, vomiting and fever. Blood analysis revealed elevated systemic inflammatory markers, and an abdominal computed tomography scan revealed non-specific alveolar condensation of the right pulmonary base and pericardial effusion subsequently quantified as medium size by transthoracic echocardiography.
A fragment of type VI collagen alpha-6 chain is elevated in serum from patients with atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus and melanoma.
Sci Rep
February 2023
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Extracellular matrix (ECM) remodeling of the skin is a continuous process necessary for maintaining tissue homeostasis. Type VI collagen (COL6) is characterized as a beaded filament, located in the dermal ECM, where COL6-α6-chain has been demonstrated upregulated in atopic dermatitis. The aim of this study was to develop and validate a competitive ELISA, targeting the N-terminal of COL6-α6-chain, named C6A6, and evaluate its associations with the dermatological condition's atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus, systemic sclerosis, urticaria, vitiligo, and cutaneous malignant melanoma in comparison, to healthy controls.
View Article and Find Full Text PDFAn Analysis of the Spatial Development of European Cities Based on Their Geometry and the CORINE Land Cover (CLC) Database.
Int J Environ Res Public Health
January 2023
Department of Geoinformation and Cartography, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, Prawocheńskiego 15, 10-720 Olsztyn, Poland.
The study demonstrated that the rate of spatial development is correlated with its fractal dimension. The presented results indicate that the fractal dimension can be a useful tool for describing different phases of urban development. Therefore, the formulated research hypothesis states that the fractal dimension of cities' external boundaries is correlated with the rate of spatial development in urban areas.
View Article and Find Full Text PDFThe effect of treatment on insight in psychotic disorders - A systematic review and meta-analysis.
Schizophr Res
June 2022
Brighton and Sussex Medical School, University of Sussex, UK. Electronic address:
Background: For people with a psychotic disorder lack of insight can be detrimental on their condition and recovery. For this reason, insight has been considered as a target for therapy. We conducted a systematic review of the literature on pharmacological, psychological and other treatments to test the hypothesis that these interventions could improve insight.
View Article and Find Full Text PDF"Should WE Stand Together?": A systematic review and meta-analysis of the effectiveness of family-based interventions for adults with chronic physical diseases.
Fam Process
December 2021
Center for Health Technology and Services Research (CINTESIS.UA), School of Health Sciences, University of Aveiro, Aveiro, Portugal.
Family support has been identified as an important factor for the psychological adjustment of patients with chronic physical conditions. This study aimed to systematically review and conduct a meta-analysis of studies comparing the effectiveness of family-based versus patient-oriented interventions for chronic physical conditions. The search was performed between April 12 and April 29, 2021, on Web of Science (all databases included), Scopus, PsycINFO, and CENTRAL.
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