AI Article Synopsis
- A study evaluated how different cell cultures responded to heat-labile enterotoxins (LT) and Verocytotoxin (VT) from fifteen E. coli strains linked to pig colibacillosis in Poland.
- Only a few cell cultures (CHO, Vero, GMK, and HeLa) were found to be susceptible to the toxins, with significant effects seen in HeLa and CHO cells.
- Results indicated that some E. coli strains from pigs produced VT enterotoxin, causing observable changes in cell structure, such as rounding and dissolution in Vero and GMK cells.
Article Abstract
The sensitivity of various cell cultures to heat-labile enterotoxins (LT) and Verocytotoxin (VT) of fifteen E. coli strains isolated from cases of pig colibacillosis in Poland was estimated and compared with the effect of enterotoxins of four standard E. coli strains. Of ten tested cell cultures, only the following were susceptible: CHO, Vero, GMK, and HeLa. Eight strains showed CTE in He La and CHO cells and five of these reacted in Vero cells. The results appear to suggest that some of the tested E. coli strains isolated from pigs produced VT enterotoxin. Morphological changes caused by the above mentioned E. coli toxins in Vero and GMK cells took the form of cell rounding, followed by cell dissolution.
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| http://dx.doi.org/10.1080/01652176.1983.9693872 | DOI Listing |
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