A biological and clinical survey was conducted in 25 patients with bancroftian filariasis, consulting the El Nikhela Health Centre, Assiout Governorate, Upper Egypt. Eleven patients showed asthmatic bronchitis. According to parasitological and serological data (specific antibodies level, total IgE), those clinical manifestations cannot be considered as a part of the "eosinophilic lung" syndrome. In this area, where Wuchereria bancrofti has been recently introduced and where there is an increasing degree of infection, bancroftian filariasis seems to predispose to allergic manifestations.
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J Family Med Prim Care
November 2024
Department of Pathology, Government Doon Medical College, Dehradun, Uttarakhand, India.
We report an interesting case of Bancroftian filariasis diagnosed on fine needle aspiration cytology in a young female hailing from a non-endemic hilly area of India, who presented with a subcutaneous swelling on the left forearm. This is an unusual extra-lymphatic site to harbor filarial infestation and the cytology smears showed adult worms, eggs, and microfilariae of .
View Article and Find Full Text PDFInt J Mycobacteriol
October 2024
Programme Department, RedAid, Enugu, Enugu State, Nigeria.
Background: Neglected tropical diseases (NTDs) significantly impact the physical and mental well-being of affected individuals, particularly in Nigeria. This study aims to evaluate the effectiveness of integrating mental health services with self-care practices for individuals suffering from leprosy, Buruli ulcer (BU), and lymphatic filariasis (LF). The role of trained Healthcare Workers (HCWs) and NTD champions (NTD-Cs) will be explored to enhance health outcomes in this population.
View Article and Find Full Text PDFBMC Infect Dis
December 2024
Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, UP, 221005, India.
Background: Lymphatic Filariasis (LF) is a neglected tropical disease affecting more than 882 million people in 44 countries of the world. A multi-epitope prophylactic/therapeutic vaccination targeting filarial defense proteins would be invaluable to achieve the current LF elimination goal.
Method: Two groups of proteins, namely Anti-oxidant (AO) and Heat shock proteins (HSPs), have been implicated in the effective survival of the filarial parasites in their hosts.
PLoS Negl Trop Dis
December 2024
Department of Entomology and Nematology, University of Florida, Gainesville, Florida, United States of America.
Background/methodology: Despite progress using mass drug administration (MDA), lymphatic filariasis (LF) remains a major public health issue in India. Vector control could potentially augment MDA towards LF elimination. We conducted a cost-effectiveness analysis of MDA alone and MDA together with vector control single (VCS) modality or vector control integrated (VCI) modalities.
View Article and Find Full Text PDFPLoS One
December 2024
UQ Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
Introduction: Lymphatic filariasis (LF) is a neglected tropical disease caused by parasitic worms, transmitted via mosquito bites. Significant global efforts have led to the interruption of LF transmission, with eight of the 16 previously endemic Pacific Island countries and territories (PICTs) validated by WHO as having eliminated the disease as a public health problem. Post-validation surveillance (PVS) is recommended to verify the absence of a resurgence in transmission; however, there are no guidelines on how to implement such surveillance effectively.
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