A reference table is presented for rapid determination of 50% lethal doses or 50% infective doses after administering 10-fold serial dilutions of toxins, viruses, sera, etc., to six animals per dilution.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272722PMC
http://dx.doi.org/10.1128/jcm.17.4.702-703.1983DOI Listing

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