During 1980 and 1981, an epidemiological survey (biotyping, serotyping, beta-lactamase production) of Haemophilus strains isolated in our hospital was performed. One hundred sixty-one Haemophilus were isolated among 146 patients: 17 H. parainfluenzae and 144 H. influenzae. Most of the infections occurred in patients, under 3 years old (77%), during cold weather (63%), and in males (55%). Biotypes I, II and III were the most common isolates (88%). Capsulated strains were frequent (53%). A beta-lactamase occurred in 9, 5% of cases. Distribution of serotypes and biotypes will be discussed in relation to clinical findings (meningitis: 21, septicemia from other origins: 9, arthritis: 2, and other non-systemic infections).
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Sci Rep
January 2025
Spobiotic Research Center, ANABIO R&D Ltd. Company, No. 22, Lot 7,8 Van Khe Urban, La Khe, Ha Dong, Hanoi, Vietnam.
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Department of Internal Medicine, Hiroshima City Funairi Citizens Hospital, Hiroshima, JPN.
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January 2025
Department of Biological Sciences, Faculty of Science, King AbdulAziz University, Jeddah, Saudi Arabia.
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January 2025
Infectious Diseases Translational Research Program, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
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View Article and Find Full Text PDFHeliyon
January 2025
Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
(, Hi) is an opportunistic bacterium that colonizes the upper respiratory tract of humans and frequently causes meningitis, pneumonia, sepsis, and other severe infections in children. Early and accurate detection of is essential for effective diagnosis and treatment. In this study, we established a novel diagnostic method by integrating the CRISPR-Cas12a detection platform with multiple cross-displacement amplification (MCDA), termed the Hi-MCDA-CRISPR assay.
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