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[Treatment quality with and without an electronic cognitive aid for emergencies in anaesthesia (eGENA) : The DANGER pilot study part 2 in randomized controlled in-situ emergency simulations].
Anaesthesiologie
January 2025
Abteilung für Anästhesie und operative Intensivmedizin, Krankenhaus Vilshofen, Vilshofen, Deutschland.
Background: The electronic cognitive aid for emergencies in anesthesia (eGENA) is an app that offers digital support in anesthesiological emergency situations as a cognitive aid tool via checklists for memory and making decisions. The eGENA was published by the German Society of Anesthesiology and has been implemented in the emergency management of the anesthesiological team of the clinic in Potsdam, Germany.
Objective: The primary endpoint was to observe the influence of eGENA on the anesthesiological emergency management on the subjective feeling of assurance as well as on quality of treatment and, therefore, patient safety.
Early and concomitant administration of norepinephrine and ilomedin improves microcirculatory perfusion without impairing macrocirculation in an intestinal ischemia-reperfusion injury swine model : a randomized experimental trial.
Shock
December 2024
Division of Anesthesiology, Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Article Synopsis
- Intestinal ischemia-reperfusion injury can lead to both large-scale (macrocirculatory) and small-scale (microcirculatory) blood flow failures, and the study aimed to test if combining a vasoconstrictor (norepinephrine) with a vasodilator (ilomedin) improves blood pressure and circulation after injury.
- The research was conducted on 21 pigs, with three groups receiving different treatments before and after a 2-hour induced small bowel ischemia followed by reperfusion, measuring various circulatory parameters and biomarkers.
- Results showed no significant differences in mean arterial pressure or cardiac index between the groups, but the combination therapy group had notably better microcirculation performance immediately after and two
Metabolic Effects of Sodium Thiosulfate During Resuscitation from Trauma and Hemorrhage in Cigarette-Smoke-Exposed Cystathionine-γ-Lyase Knockout Mice.
Biomedicines
November 2024
Institute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Background: Acute and chronic pre-traumatic cigarette smoke exposure increases morbidity and mortality after trauma and hemorrhage. In mice with a genetic deletion of the HS-producing enzyme cystathione-γ-lyase (CSE), providing exogenous HS using sodium thiosulfate (NaSO) improved organ function after chest trauma and hemorrhagic shock. Therefore, we evaluated the effect of NaSO during resuscitation from blunt chest trauma and hemorrhagic shock on CSE mice with pre-traumatic cigarette smoke (CS) exposure.
View Article and Find Full Text PDFBrainstem Anesthesia and Cardiac Arrest Following Peribulbar Block: A Case Report and Systematic Review of the Literature.
J Clin Med
November 2024
Department of Ophthalmology, Sankara Eye Hospital, Jaipur 302039, Rajasthan, India.
: We report a case of brainstem anesthesia (BSA) and subsequent cardiac arrest following a routinary peribulbar block (PB) in a patient scheduled for cataract extraction and intraocular lens (IOL) implantation, thus providing a reference for further analysis of this potentially catastrophic life-threatening complication and to evaluate the current knowledge in terms of incidence, physiopathology management, and treatment of the BSA following PB. : Three databases (PubMed, Embase, and Scopus) were checked to perform a systematic review of all available studies in the English Language following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to evaluate relevant studies that clearly described BSA following BSA. : Our literature search identified 15 cases.
View Article and Find Full Text PDFCombined robotic surgery for concomitant treatment of endometrial cancer and obesity.
Surg Endosc
November 2024
Division of Oncologic Gynecology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Background: Endometrial Cancer (EC) is strongly linked to obesity. Bariatric surgery is recognized as a long-term solution for weight loss in severely obese patients. This pilot study investigates the feasibility, intraoperative and 30-day morbidity outcomes of integrating gynecological surgical staging and bariatric robotic surgery in class II and III obese patients affected by early EC or Endometrial Intraepithelial Neoplasia (EIN).
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