Quantitation of interleukin 1 production by adherent mononuclear cells from peripheral blood was performed in patients with tuberculoid and lepromatous forms of leprosy. Cells from patients with tuberculoid leprosy either secreted interleukin 1 spontaneously or produced amounts within the normal range in response to lipopolysaccharide stimulation. Conversely, stimulated cells from lepromatous patients failed to produce interleukin 1 in 5 of 13 (38.5%) cases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC263369PMC
http://dx.doi.org/10.1128/iai.45.3.787-789.1984DOI Listing

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