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BMC Genomics
December 2024
School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy Campus, Roseworthy, South Australia, 5371, Australia.
Background: Fat traits in cattle are considered important due to their contribution to beef eating quality and carcass economic value. Discovering the genes controlling fat traits in cattle will enable better selection of these traits, but identifying these genes in individual experiments has proven difficult. Compared to individual experiments, meta-analyses allow greater statistical power for detecting quantitative trait loci and identifying genes that influence single and multiple economically important fat traits.
View Article and Find Full Text PDFElife
December 2024
Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, United States.
Organ function declines with age, and large-scale transcriptomic analyses have highlighted differential aging trajectories across tissues. The mechanism underlying shared and organ-selective functional changes across the lifespan, however, still remains poorly understood. Given the central role of mitochondria in powering cellular processes needed to maintain tissue health, we therefore undertook a systematic assessment of respiratory activity across 33 different tissues in young (2.
View Article and Find Full Text PDFCureus
October 2024
Orthopaedic Surgery, Unit-II, Sheikh Zayed Medical College Rahim Yar Khan, Rahim Yar Khan, PAK.
Cardiovasc Diabetol
October 2024
Department of Clinical Physiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Epicardial adipose tissue (EAT) is a unique fat depot located between the myocardium and the visceral layer of pericardium. It can be further subdivided into pericoronary (PCAT), periatrial (PAAT) and periventricular adipose tissue (PVentAT), each of them exhibiting specific characteristics and association with the underlying tissue. Since no physical barrier separates EAT from the myocardium, this fat tissue can easily interact with the underlying cardiac structure.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
September 2024
Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, 710004, Shaanxi, China.
Context: Different fat depots have connected to cardiovascular health.
Objective: We assessed the associations of abdominal magnetic resonance-quantified visceral adipose tissue (VAT) and liver fat (proton density fat fraction, PDFF) with cardiac magnetic resonance (CMR)-measured cardiac structure and function, and considered potential mechanism.
Methods: Our study encompassed 10,920 participants from the UK Biobank.
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