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Article Synopsis
- A new viral species called human circovirus (HCirV) has been identified, potentially linked to hepatitis in people with weakened immune systems.
- A study tested 278 hepatitis patients and 184 healthy individuals, finding HCirV in 2.9% of the hepatitis patients but none in healthy individuals.
- The virus appears to have a preference for liver cells, indicated by its ability to bind to liver cancer cell lines but not to lung cells, suggesting it may play a role in hepatitis, especially in immunocompromised patients.
When Histiocytosis Masquerades as Mononucleosis: A Case Report.
Cureus
September 2024
Infectious Diseases, New Hospitals, Tbilisi, GEO.
Article Synopsis
- Langerhans cell histiocytosis (LCH) is a rare childhood disorder with diverse symptoms, making early diagnosis challenging.
- Biopsy and specific molecular testing are often needed for confirmation, which may not be available in all medical facilities.
- A case of a two-year-old girl misdiagnosed with infectious mononucleosis underscores the need for better awareness of LCH in clinical practice to improve timely treatment.
Extensive Cytomegalovirus Gastroduodenitis Causing Gastric Outlet Obstruction in an Immunocompetent Patient.
ACG Case Rep J
July 2024
Department of Pathology, Aga Khan University Hospital, Karachi, Pakistan.
Cytomegalovirus (CMV) has been extensively researched in immunocompromised people, causing conditions such as colitis, retinitis, esophagitis, encephalitis, and pneumonitis. However, there are limited data on how the disease presents itself in immunocompetent hosts, apart from a self-limited mononucleosis-like syndrome. This case report presents CMV gastroenteritis causing gastroduodenal obstruction in an immunocompetent woman.
View Article and Find Full Text PDFPosttransplant Lymphoproliferative Disorder in a Patient With Alpha-1 Antitrypsin Deficiency: A Case Report.
Cureus
June 2024
Pediatric Medicine, Gadsden Pediatric Clinic, Gadsden, USA.
A 13-year-old male with a past medical history of receiving a whole liver transplant secondary to alpha-1 antitrypsin deficiency (AATD) with subsequent inferior vena cava thrombosis nine years prior presented to the emergency department with abdominal distension, shortness of breath, coughing, and left superficial cervical lymphadenopathy. He had seen his pediatrician the day before where he tested negative for group A , influenza, and severe acute respiratory syndrome coronavirus 2. Additionally, the patient reported having elevated liver function tests noted from the results of lab tests taken earlier that day.
View Article and Find Full Text PDFEnhancing indicator condition-guided HIV testing in Taiwan: a nationwide case-control study from 2009 to 2015.
BMC Public Health
April 2024
Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C..
Background: Although indicator condition (IC)-guided HIV testing (IC-HIVT) is effective at facilitating timely HIV diagnosis, research on IC categories and the related HIV risk in Taiwan is limited. To improve the adoption and spread of IC-HIVT in Taiwan, this study compared the IC categories of people living with HIV (PLWH) and non-HIV controls and investigated delays in the diagnosis of HIV infection.
Methods: This nationwide, retrospective, 1:10-matched case-control study analyzed data from the Notifiable Diseases Surveillance System and National Health Insurance Research Database to evaluate 42 ICs for the 5-year period preceding a matched HIV diagnostic date from 2009 to 2015.
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