The authors report eleven new cases of nephrogenic metaplasia - a substantial addition to the sixty-three cases already reported in the literature. In their series, two cases involved the ureter, and nine, the bladder. They discuss the clinical and pathological aspects of the disease, and put forward suggestions concerning different aspects of the histogenesis. They consider the possibility of introducing new terminology.
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Nephrogenic adenoma of the urinary bladder is a rare, benign lesion associated with prior inflammation or irritation of the urothelium. Although typically benign, nephrogenic adenoma can present diagnostic challenges due to its potential to mimic malignant tumors of the urinary tract. In this report, we present a case of an elderly woman with a history of recurrent urinary tract infections and bladder stone surgery who developed nephrogenic adenoma.
View Article and Find Full Text PDFNephrogenic Adenoma: A Pitfall on Frozen Section of Urethral Strictures.
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October 2024
Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Canada.
Urethral strictures are a common cause of urinary obstruction which can be treated with surgical resection. Frozen sections are rare and pose a diagnostic challenge to pathologists due to the presence of benign lesions such as nephrogenic adenoma. We retrospectively examined all specimens of urethral stricture resections submitted to pathology at our institution from 2012 to 2022 (n = 258).
View Article and Find Full Text PDFDiagnostic Approach to and Differential Diagnosis of Clear Cell and Glandular Lesions of the Lower Urinary Tract.
Arch Pathol Lab Med
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From the Department of Pathology, University of Michigan Medical School, Ann Arbor.
Context.—: A variety of glandular and clear cell lesions may be seen in the urinary bladder and/or urethra, ranging from benign to malignant primary and secondary tumors. Lesions with no malignant potential include reactive processes, such as nephrogenic metaplasia, and may show similar morphologic features as an infiltrative neoplasm, particularly in small biopsies.
View Article and Find Full Text PDFBilateral Ureteral Nephrogenic Adenoma: An Unusual Mimicker of Malignancy.
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Urology, Wye Valley NHS Trust, Hereford, GBR.
Nephrogenic adenoma (NA) is a rare, benign lesion of the urinary tract that is induced by chronic irritation or injury to the urinary tract. Ureteral nephrogenic adenoma arising from both ureters is an exceptionally rare condition. We report an unusual case of a 73-year-old male who presented with a several-month history of recurrent UTI-like symptoms.
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