A catabolite repression-resistant mutant of the thermophilic actinomycete Thermomonospora curvata was obtained by treatment with ethyl methanesulfonate and UV light. Cellulase biosynthesis was undiminished by glucose, 2-deoxyglucose, or alpha-methyl glucoside, which are potent repressors in the wild type. Intracellular cyclic AMP levels were higher in the mutant in both the absence and the presence of repressors.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC239637 | PMC |
| http://dx.doi.org/10.1128/aem.47.1.201-204.1984 | DOI Listing |
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