3-[(2,3-Cyclopenteno-1-pyridinium)-methyl]-7-[2-syn-methoximino-2-(2-aminothiazol-4-yl)-acetamido]-ceph-3-em-4-carboxylate (HR 810) is a new cephalosporin derivative with an extremely broad antimicrobial spectrum. It is active against all bacterial species of clinical relevance, including strains which are frequently resistant towards cephalosporins of the third generation.
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- * 60 thalassemia patients were divided into three groups based on their chelation treatments: oral deferiprone daily, subcutaneous deferoxamine four times weekly, and a combination of both therapies.
- * Results show that the combination therapy was the most effective in reducing iron levels and improving urinary iron excretion, while patients on deferoxamine had the least hepatic iron deposition, though still above normal levels.
Iron deficiency, supplementation, and sports performance in female athletes: A systematic review.
J Sport Health Sci
November 2024
Research Institute for Sport and Exercise (UCRISE), University of Canberra, Canberra ACT 2617, Australia.
Background: Iron facilitates key biological functions underpinning sports performance, and up to 60% of female athletes experience iron deficiency. However, the effects of iron deficiency on sports performance in female athletes is unclear, as are the degree of benefits of iron supplementation (FeSup). This study characterizes the effects of iron deficiency and FeSup on sports performance in high-level female athletes.
View Article and Find Full Text PDFUse of Prophylactic Parenteral Tranexamic Acid for Reduction of Blood Loss During and After Caesarean Section: A Double-Blind Randomized Controlled Study.
West Afr J Med
July 2024
Department of Haematology and Immunology, University of Nigeria Teaching Hospital Ituku-Ozalla, Enugu.
Background: Haemorrhage is a leading cause of maternal mortality. The prophylactic use of tranexamic acid during vaginal delivery or caesarean section has the potential to reduce blood loss and postpartum anaemia.
Objective: To determine the effectiveness and safety of tranexamic acid in reducing blood loss during and within twenty-four hours after a caesarean section.
Safety and quality of parenteral nutrition: Areas for improvement and future perspectives.
Am J Health Syst Pharm
June 2024
Department of Anesthesiology and Surgery, Duke University School of Medicine, Durham, NC, USA.
Purpose: This article is based on presentations and discussions held at the International Safety and Quality of Parenteral Nutrition (PN) Summit (held November 8-10, 2021, at Charleston, SC, and Bad Homburg, Germany) and aims to raise awareness concerning unresolved issues associated with the PN process and potential future directions, including a greater emphasis on patients' perspectives and the role of patient support.
Summary: Ensuring that every patient in need receives adequate PN support remains challenging. It is important to have a standardized approach to identify nutritional risk and requirements using validated nutritional screening and assessment tools.
Plasma and red blood cell concentrations of zinc, copper, selenium and magnesium in the first week of paediatric critical illness.
Clin Nutr
February 2024
Department of Neonatal and Paediatric Intensive Care, Division of Paediatric Intensive Care, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands. Electronic address:
Background & Aims: Critically ill children are at risk of micronutrient deficiencies, which might lead to poor clinical outcomes. However, the interpretation of micronutrient concentrations in plasma is complicated due to age-dependent and critical illness-dependent changes. Certain red blood cell (RBC) concentrations might reflect the overall body status more reliably than plasma levels in the presence of systemic inflammatory response.
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