Analyses of the 5' ends of snowshoe hare bunyavirus plus sense S RNA species (including mRNA) recovered from infected cells have revealed two types of termini. These include ends that are essentially exact copies of the 3' end of the viral S RNA and others that are similar, but additionally have 13-14 nucleotide extensions that are heterogeneous in sequence. The former probably represent replicative plus sense RNA species, the latter mRNA species that have host cell derived primer sequences.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC326382PMC
http://dx.doi.org/10.1093/nar/11.18.6409DOI Listing

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