Seventy cases of myomectomy performed over 5 years (1977 to 1982) in the department of Gynecology & Obstetrics of the St Antoine Hospital in Paris are analyzed. During the same period, 465 patients underwent hysterectomy for leiomyoma. A brief review shows that myomectomy is not the best surgical treatment of uterine leiomyoma because of its complications. Hemorrhagy, pelvic pain and infertility remain the principle modes of discovery of uterine leiomyoma in operated patients, whose median age is fairly low. Hysterosalpingography is still the main procedure for the investigation and diagnosis of leiomyoma. However, indications of echotomography have been extended with an increase in the frequency of diagnosis of leiomyoma due to a better semiology. Primary leiomyoma section followed by excision appears preferable to conventional enucleation, which is frequently hemorrhagic and blind. In determining the indications of myomectomy, certain factors must be borne in mind: age, parity, type and insertion of leiomyoma, gynecologic history and psychological status. Good postoperative results explain the recent favor of myomectomy as the conservative surgical treatment of leiomyoma; surgical abstention, however, remains the best decision in most cases.
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Case Rep Obstet Gynecol
January 2025
Department of Medicine, Ethio Tebib Hospital, Addis Ababa, Ethiopia.
Müllerian duct anomalies and uterine leiomyomas represent distinctive facets of female reproductive health. While uterine leiomyomas are prevalent reproductive pathologies, the coexistence of Müllerian anomalies and leiomyomas is relatively uncommon. This case study examines the complex medical and surgical management of a woman who initially presented with chronic abdominal pain and swelling.
View Article and Find Full Text PDFJ Pharm Biomed Anal
January 2025
Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian 350005, China; FujianKey Laboratory of Women and Children's Critical Diseases Research, Fuzhou, Fujian 350005, China. Electronic address:
Isothermal, enzyme-free amplification techniques, such as the hybridization chain reaction (HCR) and catalytic hairpin assembly (CHA), have gained significant attention for mRNA analysis. Despite their potential, these methods still face challenges, including false positives and low amplification efficiency. To overcome these limitations, we have developed a confined catalytic hairpin assembly and hybridization chain reaction (CHA-HCR) system that utilizes cholesterol-modified hairpin probes to enhance the sensitivity and specificity of mRNA detection.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Department of Radiology, All India Institute of Medical Science Bhopal, Bhopal, Madhya Pradesh, India.
Pyomyoma, a rare complication of uterine artery embolisation (UAE) for symptomatic fibroids, can closely mimic post-embolisation syndrome (PES), which typically presents with pain, fever and leucocytosis within the first week. Differentiating PES from pyomyoma is critical, as pyomyoma carries a higher risk of severe complications. We report a case of an unmarried nulliparous woman who developed pyomyoma following UAE for fibroids.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
January 2025
Montefiore Medical Center/Albert Einstein College of Medicine, Division of Fetal Medicine and Ultrasound, Department of Obstetrics and Gynecology and Women's Health.
Objective: Low placentation is associated with increased risk of postpartum hemorrhage (PPH). There is a paucity of data on the association between second trimester low placentation that later resolves, and PPH. Our objective was to investigate the association of resolved low placentation and other prenatal ultrasound markers, and PPH with delivery.
View Article and Find Full Text PDFSurg Endosc
January 2025
Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, Taiwan.
Background: This study aimed to investigate the clinical characteristics and esophageal motility of patients with gastric cardia submucosal tumors (SMTs) and the associated changes after endoscopic resection based on high-resolution impedance manometry (HRIM).
Methods: From our electronic database, we identified patients who underwent pre-operative evaluation of gastric cardia SMTs between 2015 and 2023. All patients completed standardized symptom questionnaires and underwent endoscopic ultrasonography and HRIM.
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