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http://dx.doi.org/10.1111/j.1365-2184.1978.tb00887.x | DOI Listing |
Int Med Case Rep J
January 2025
National Scientific Center of Traumatology and Orthopedics Named After Academician Batpenov N.D., Astana, Kazakhstan.
Background: Cartilage defects in the knee joint are areas of damage and wear to the cartilage that normally covers and protects the ends of bones. These defects occur due to sudden injuries, such as trauma or sports accidents, or due to chronic conditions, such as osteoarthritis. Cartilage acts as a shock absorber (cushion absorber), reducing the impact of mechanical stress on the joints, which helps prevent bone damage during movement.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Surgery, St. Luke's Health System, Kansas City, MO 64108, United States of America.
Introduction And Importance: Schwannomas arise from Schwann cells, which make up the neural sheath of peripheral nerves. These tumors are usually seen in the head, neck and flexor surfaces, but can arise in the retroperitoneal space on rare occasions. This case gives the unique opportunity to watch the long term progression and speed of growth of this rare tumor and the development of symptoms over time.
View Article and Find Full Text PDFAvicenna J Med Biotechnol
January 2024
Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Chronic Lymphocytic Leukemia (CLL) is a clinically and biologically heterogeneous disease with a variable clinical course. The induction of a generalized state of immuno-suppression, leading to susceptibility to infections and the failure of anti-tumor immune responses, is a key feature of the clinical course of CLL. In addition to B-cell receptor (BCR) signaling in CLL, several receptor tyrosine kinases (RTKs) have been reported to be constitutively active in leukemic B cells, resulting in promoted survival and resistance to apoptosis induced by chemotherapy.
View Article and Find Full Text PDFElife
November 2024
Department of Experimental Oncology, European Institute of Oncology-IRCCS, Milan, Italy.
Future Sci OA
December 2024
Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Immune checkpoint inhibitors (ICIs) have gained widespread application in the treatment of malignant tumors. Cytokine release syndrome (CRS) is a systemic inflammatory response triggered by various factors, including infections and immunotherapy. We present a case of CRS occurring in a gastric cancer patient after receiving combination therapy of tislelizumab, anlotinib and combination of capecitabine and oxaliplatin.
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