In 1978--1979, four cases of encephalomyocarditis were recorded in baboons in a simian preserve of the USSR AMS Research Institute of Experimental Pathology and Therapy located in the Zapadnyaya Gumista river valley. The diagnosis was made on the basis of virological and pathomorphological examinations. The isolate recovered from the dead monkeys was identical with the prototype strain of encephalomyocarditis virus (EMC) and the EMC-70 strain previously isolated by us from M. rhesus monkeys. The infection of monkeys caused by the EMC-78/79 virus involved a severe affection of the myocardium of the type of parenchymatous-interstitial myocarditis, moderate encephalitis in the central nervous system, inflammatory changes in the brown fat and cross-striated muscles. An experimental infection in guinea pigs and mice exhibited similar features.
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Virus Res
January 2018
D. I. Ivanovsky Institute of Virology, N. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia. Electronic address:
In 2007, numerous hamadryas baboons (Papio hamadryas) died suddenly in an aviary of a primate institute in Sochi, Russia, in the absence of prior clinical signs. Necropsies were suggestive of encephalomyocarditis virus infection, but RT-PCR assays with commonly used primers were negative. Here we report the histopathological results obtained during necropsies and the isolation and genomic characterization of a divergent strain of encephalomyocarditis virus 1 (EMCV-1) from heart tissue of one of the succumbed hamadryas baboons.
View Article and Find Full Text PDFIn 1978--1979, four cases of encephalomyocarditis were recorded in baboons in a simian preserve of the USSR AMS Research Institute of Experimental Pathology and Therapy located in the Zapadnyaya Gumista river valley. The diagnosis was made on the basis of virological and pathomorphological examinations. The isolate recovered from the dead monkeys was identical with the prototype strain of encephalomyocarditis virus (EMC) and the EMC-70 strain previously isolated by us from M.
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