180 male Wistar-rats were daily exposed to 30 and 100 mg MNNG/1000 ccm tapwater. After 7 weeks exposure a truncal vagotomy with pyloroplasty or a Billroth-II-resection was performed in 25 animals of each dosage-group. 80 rats were not operated. The incidence of carcinomas in the Billroth-II-rats of both dosage-groups was evidently higher than in the exposed controls. In the vagotomized rats an increased occurrence of carcinomas could not be observed.

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