Out outbreak of goat pox occurred among 60 adult and young goats in the Sudan. Among the findings of special interest was the extensive and wide distribution of pox lesions on the bodies of the animals. The severe involvement of the mucous membranes of the muzzle, eyes and nostrils gave rise to acute respiratory distress and systemic reaction. The suppression of secondary bacterial infection with local and systemic terramycin in addition to supportive therapy of affected animals alleviated the condition and none of the animals died. Typical pox lesions were produced experimentally on goats and sheep using infected material from goats. Human infections were not encountered.
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http://dx.doi.org/10.1007/BF02282593 | DOI Listing |
Virology
December 2024
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, PR China. Electronic address:
Capripoxviruses (CaPVs), such as lumpy skin disease, sheep pox, and goat pox, cause significant production and economic losses and are major constraints to the growth of livestock production in endemic areas. Understanding the pathogenic mechanism of CaPVs and their translation into clinical applications depends on the availability of a suitable cell line. In this study, we used a lentiviral packaging system to establish an immortalized hTERT-bOEC cell line by ectopic introduction of human telomerase reverse transcriptase (hTERT).
View Article and Find Full Text PDFBMC Vet Res
December 2024
Animal Pathology Department, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Veterinary Faculty of Zaragoza, C/Miguel Servet 177, Zaragoza, 50013, Spain.
Background: Infectious diseases, particularly the Goatpox virus (GTPV) from the Poxviridae family, significantly impact livestock health and agricultural economies, especially in developing regions. Recent GTPV outbreaks in previously eradicated areas underscore the need for effective control measures, with vaccination being the most reliable strategy. This study investigates the effects of administering standard and double doses of live attenuated goatpox vaccine in pregnant Murcia-Granada goats, a non-native breed in Iran, to determine optimal vaccination protocols.
View Article and Find Full Text PDFFront Vet Sci
November 2024
Key Laboratory of Animal Medicine of Sichuan Province, College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Introduction: Monkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health. Clinical diagnostics continue to face challenges regarding specificity among poxviruses.
View Article and Find Full Text PDFAccess Microbiol
October 2024
The Pirbright Institute, Ash Road, Pirbright, Surrey, UK.
Multiple transboundary animal diseases (TADs) circulate in Plateau State, Nigeria, where livestock keeping is common and contributes to both the physical and socio-economic well-being of a large proportion of the population. In this study, we explored the potential for environmental sampling to detect viruses causing TADs circulating in the region. Electrostatic dust cloths were used to swab areas of the environment likely to have contact with secretions and excretions from infected animals.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2024
China Institute of Veterinary Drug Control, Beijing, China.
P32 protein serves as a crucial structural component of Goat pox virus (GTPV), which causes a highly virulent infectious disease in sheep and goats. Despite the fact that P32 has been widely expressed in the previous studies, it is difficult to obtain recombinant P32 efficiently. This study aimed to achieve soluble expression of P32 recombinant protein and to develop its specific monoclonal antibody.
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