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Successful surgical management of esophageal leiomyoma presenting with gastroesophageal reflux disease symptoms: A case report.
Int J Surg Case Rep
December 2024
Gastroenterology Department, Al Ahli Hospital, Hebron 90200, Palestine.
Introduction: Esophageal leiomyoma is the most common benign submucosal mesenchymal tumor of the esophagus, typically asymptomatic but can cause symptoms such as dysphagia, chest pain, or regurgitation when large. Diagnosis is often incidental, confirmed by imaging techniques like computed tomography (CT) and endoscopic ultrasound (EUS), with surgical enucleation being the standard treatment.
Presentation Of Case: A 28-year-old male presented with a one-year history of persistent epigastric discomfort and gastroesophageal reflux disease (GERD) symptoms unresponsive to proton pump inhibitors.
A drug-drug co-amorphous system for highly improved solubility of breviscapine: an experimental and computational study.
Sci Rep
December 2024
College of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming, 650500, China.
Drug-drug co-amorphous systems are a promising approach to improve the aqueous solubility of poorly water-soluble drugs. This study explores the combination of breviscapine (BRE) and matrine (MAT) form an amorphous salt, aiming to synergistically enhance the solubility and dissolution of BRE. In silico analysis of electrostatic potential and local ionization energy were conducted on BRE-MAT complex to predict the intermolecular interactions, and solvent-free energies were calculated using thermodynamic integration and density functional theory.
View Article and Find Full Text PDFDual-biased metal oxide electrolyte-gated thin-film transistors for enhanced protonation in complex biofluids.
Sci Rep
December 2024
Department of Electrical and Computer Engineering, Ajou University, Suwon, 16499, Republic of Korea.
pH sensing technology is pivotal for monitoring aquatic ecosystems and diagnosing human health conditions. Indium-gallium-zinc oxide electrolyte-gated thin-film transistors (IGZO EGTFTs) are highly regarded as ion-sensing devices due to the pH-dependent surface chemistry of their sensing membranes. However, applying EGTFT-based pH sensors in complex biofluids containing diverse charged species poses challenges due to ion interference and inherently low sensitivity constrained by the Nernst limit.
View Article and Find Full Text PDFA method for comparing MRI sequences of the knee for segmentation based on morphological features.
PLoS One
December 2024
Department of Materials and Production, Aalborg University, Aalborg, Denmark.
Background: In magnetic resonance imaging (MRI) segmentation research, the choice of sequence influences the segmentation accuracy. This study introduces a method to compare sequences. By aligning sequences with specific segmentation objectives, we provide an example of a comparative analysis of various sequences for knee images.
View Article and Find Full Text PDFDeep eutectic solvent pretreatment of oil palm biomass: Promoted lignin pyrolysis and enzymatic digestibility of solid residues.
Int J Biol Macromol
December 2024
Beijing Key Laboratory of Lignocellulosic Chemistry, Beijing Forestry University, Beijing 100083, PR China. Electronic address:
Herein, choline chloride/oxalic acid (ChCl/OA) and choline chloride/oxalic acid/ethylene glycol (ChCl/OA/EG) pretreatments of oil palm empty fruit bunches (EFB) and mesocarp fibers (MSF) were conducted to achieve protection of the lignin structure, while improving the enzymatic efficiency of the solid residues. Under the operating conditions of 90 °C and 6 h, ChCl/OA/EG demonstrated a higher lignin extraction selectivity and obtained solid residues with higher hemicellulose content compared to ChCl/OA. The digestibility of glucan and xylan in solid residues obtained using ChCl/OA/EG achieved 98.
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