Rous sarcoma virus (RSV) isolated from virogenic transformed hamster cells differed from the original Schmidt-Ruppin strain used to inoculate hamster embryo fibroblasts in the capacity to effectively transform mammalian cells, to multiply in these cells, in the reduced reproductive activity in chicken cells. These altered properties were relatively stable since they were retained in the first virus passages in chickens.
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Introduction: Around 85% of non-small cell lung cancers (NSCLCs) are diagnosed at an advanced stage (IIIB to IV), where therapeutic options depend on molecular analysis. However, diagnostic material for molecular testing is often represented by cytological samples which are generally scarce and span a wide range of preparation types. Thus, the primary objective is to efficiently manage materials for molecular profiling.
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Department of Medicine, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA.
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