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Dexamethasone ameliorates the damage of hippocampal filamentous actin cytoskeleton but is not sufficient to cease epileptogenesis in pilocarpine induced epileptic mice.
Epilepsy Res
August 2019
Department of Pediatric Neurology, The First Hospital of Jilin University, Changchun, Jilin Province 130021, PR China. Electronic address:
Rogressive deconstruction of filament actin (F-actin) in hippocampal neurons in the epileptic brain have been associated with epileptogenesis. Previous clinical studies suggest that glucocorticoids treatment plays beneficial roles in refractory epilepsy. Glucocorticoids treatment affects dendritic spine morphology by regulating local glucocorticoid receptors and F-actin cytoskeleton dynamics.
View Article and Find Full Text PDFRecent Advances in RAFT Polymerization: Novel Initiation Mechanisms and Optoelectronic Applications.
Polymers (Basel)
March 2018
Key Laboratory for Advanced Materials and Shanghai Key Laboratory of Functional Materials Chemistry, Institute of Applied Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Reversible addition-fragmentation chain transfer (RAFT) is considered to be one of most famous reversible deactivation radical polymerization protocols. Benefiting from its living or controlled polymerization process, complex polymeric architectures with controlled molecular weight, low dispersity, as well as various functionality have been constructed, which could be applied in wide fields, including materials, biology, and electrology. Under the continuous research improvement, main achievements have focused on the development of new RAFT techniques, containing fancy initiation methods (e.
View Article and Find Full Text PDFOne-pot colloidal chemistry route to homogeneous and doped colloidosomes.
J Am Chem Soc
September 2013
Division of Nanomaterials and Chemistry, Hefei National Laboratory for Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China.
Colloidosomes are usually produced from a series of building blocks with different sizes ranging from several nanometers to micrometers or various shapes, such as particles, microrods, and quantum dots. Colloidosomes can possess a variety of characteristics in terms of photics, electrology, mechanical strength, and selective permeability, derived from their building blocks. However, poor mechanical stability and complicated synthesis processes have limited the applications of colloidosomes.
View Article and Find Full Text PDFScience and sports: a brief history of muscle, motion and ad hoc organizations.
J Sports Sci
September 2003
Department of Experimental Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, B-1090 Brussels, Belgium.
Both the history of biolocomotion (later to become motion analysis/biomechanics) and of electrology (later kinesiological electromyography) are to be traced back to approximatively the same period in the second half of the seventeenth century. The major contributors to these emergent sciences were Swammerdam in 1658 and Borelli in 1680. Some 150 years later, electrophysiological methods were derived and motion-cinephotography was developed from their pioneering work.
View Article and Find Full Text PDFThe evaluation and management of hirsutism.
Obstet Gynecol
May 2003
Departments of Obstetrics and Gynecology and Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA
Hirsutism is the presence of terminal (coarse) hairs in females in a male-like pattern, affecting between 5% and 15% of women, depending on definition. Hirsutism has a significant negative impact on psychosocial development and is usually a sign of an underlying endocrine abnormality-namely, androgen excess. The most common cause of androgen excess is the polycystic ovary syndrome (PCOS), with 21-hydroxylase-deficient nonclassic adrenal hyperplasia, the hyperandrogenic insulin-resistant acanthosis nigricans syndrome, androgen-secreting tumors, and androgenic drug intake occurring less frequently.
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