Blockade of gamma-aminobutyric acid receptor function by direct microinjection of bicuculline into the nucleus ambiguous in cats produced a marked increase in gastric motility which was mediated by the vagus nerve. This effect was reversed by muscimol. These data indicate that the nucleus ambiguous may be an important brain site influencing gastric function and that the neurotransmitter controlling parasympathetic overflow from this nucleus to the stomach is gamma-aminobutyric acid.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1126/science.6269182 | DOI Listing |
Publication Analysis
Top Keywords
gamma-aminobutyric acid
8
nucleus ambiguous
8
hindbrain gaba
4
gaba receptors
4
receptors influence
4
influence parasympathetic
4
parasympathetic outflow
4
outflow stomach
4
stomach blockade
4
blockade gamma-aminobutyric
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!