AI Article Synopsis
- The study found that giving external insulin before and after glucose delivery into the duodenum reduced the GIP hormone response to glucose.
- The levels of insulin in the blood reached normal physiological levels.
- This indicates that there is a negative feedback mechanism where the body’s own insulin regulates GIP release.
Article Abstract
Administration of exogenous insulin before and after intraduodenal glucose results in blunting of the GIP response to glucose. Physiologic levels of serum insulin were attained. Therefore, the present study suggests the existence of negative feedback regulation of GIP release by endogenous insulin (pancreatico-GIP axis).
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| http://dx.doi.org/10.1016/0002-9610(78)90088-0 | DOI Listing |
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