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Relationship between platelet distribution width and non-dipping pattern in children with essential hypertension.
BMC Pediatr
January 2025
Department of Cardiology, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Hypertension has shown a trend of prevalence at younger ages, and the non-dipping pattern is associated with target organ damage in hypertension. However, few studies have yet investigated the clinical characteristics and risk factors of non-dipper status in essential hypertension children. This study aimed to explore the clinical characteristics and possible indicators associated with non-dipper status in children with essential hypertension.
View Article and Find Full Text PDFPlatelet mass index, systemic immune-inflammation index, and neutrophil-lymphocyte ratio as practical markers in childhood brucellosis.
Rev Paul Pediatr
January 2025
Afyonkarahisar Health Sciences University, Faculty of Medicine, Department of Child Health and Diseases, Afyonkarahisar, Turkey.
Objective: Brucellosis is a multisystem infectious disease and may cause an increase in acute phase reactants. This study aimed to examine the platelet mass index (PMI), the neutrophil-lymphocyte ratio (NLR), and systemic immune-inflammation index (SII) in children with brucellosis and to determine their roles in focal involvement.
Methods: This retrospective observational study included 69 patients with brucellosis and a control group of 69 healthy children.
Increased risk of coronary artery diseases in overweight and obese individuals is partially mediated by chronic inflammation: The EPICOR study.
Nutr Metab Cardiovasc Dis
December 2024
Department of Health Sciences Università Del Piemonte Orientale, via Solaroli 17, 28100 Novara and Unit of Epidemiology, Local Health Unit of Novara, Viale Roma, 7, 28100, Novara, Italy. Electronic address:
Background And Aims: It is well known that being overweight or obese is a risk factor for coronary artery disease (CAD). At the same time, belonging to these categories indirectly influences other risk factors like hypertension, diabetes or dyslipidemia also through a chronic inflammation condition. The aim of this study was to establish to which extent the effect of body mass index (BMI) on CAD risk can be explained by the chronic inflammation degree, using a statistical mediation model.
View Article and Find Full Text PDFTransforaminal interbody debridement and fusion with antibiotic-impregnated bone graft to treat pyogenic discitis and vertebral osteomyelitis: a comparative study in Asian population.
Asian Spine J
January 2025
Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Study Design: A retrospective cohort study.
Purpose: To evaluate whether using antibiotic-impregnated bone graft (AIBG) enhances infection control and shortens the postoperative course of pyogenic discitis and vertebral osteomyelitis (PDVO).
Overview Of Literature: Surgical treatment of PDVO is indicated for neurological deficit, instability, unknown pathogen, or poorly controlled infection.
Clinical outcomes and treatment patterns of maintenance avelumab in locally advanced or metastatic urothelial carcinoma: a multicenter collaborative study.
Jpn J Clin Oncol
January 2025
Department of Urology, The Jikei University School of Medicine, 3-25-8, Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan.
Background: The JAVELIN Bladder 100 trial demonstrated improved overall survival (OS) with maintenance avelumab in patients with locally advanced or metastatic urothelial carcinoma UC (la/mUC) who achieved disease control following first-line platinum-based chemotherapy (1 L-PBC). However, real-world data on eligibility, utilization, and outcomes of maintenance avelumab therapy remain limited.
Methods: This retrospective study included patients with la/mUC who received 1 L-PBC.
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