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Accumulation of pyrophosphate and other energy-rich phosphorous compounds under various conditions of yeast growth. | LitMetric

AI Article Synopsis

  • The hybrid yeast strain Saccharomyces N.C.Y.C. 644 SU3 accumulates significant amounts of pyrophosphate, with levels 10-100 times higher than ATP, regardless of aeration and glucose levels.
  • During the early and mid-exponential growth phases, two peaks of pyrophosphate accumulation are noted, linked to minimal levels of polymeric acid-soluble polyphosphates and high rates of budding.
  • The study explores the relationship between pyrophosphate metabolism and acid-soluble polyphosphate levels in yeast.

Article Abstract

In the cells of hybrid yeast strain Saccharomyces N.C.Y.C. 644 SU3 (Karlsberg collection), a large amount of pyrophosphate (30-300 micro mol per g of dry weight) accumulates whatever the aeration conditions and the contest of glucose in the medium. The content of pyrophosphate is 10-100 times higher than that of ATP. At the early and mid-exponential growth phases two maxima of pyrophosphate accumulation are observable. The periods of maximal pyrophosphate accumulation in yeast coincide with those of the minimal contest of polymeric acid-soluble polyphosphates and intense budding. In the light of the data obtained, the question is discussed as to the relationship between the metabolism of pyrophosphates and acid-soluble polyphosphates in yeats.

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Source
http://dx.doi.org/10.1007/BF00405919DOI Listing

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