[Study of enteroviruses in different environments using guanidine-dependent variants].

Guanidine-dependent variants of enteroviruses were used as indicators for the study of the effectiveness of environmental object purification processes. The dependence of virus replication on guanidine provides complete safety of the virus for man and selective virus isolation from the objects under study. The use of the indicator virus allows to perform quantitation studies. Two examples of practical utilization of a guanidine-dependent variant of poliomyelitis virus (evaluation of the effectiveness of sewage purification from enteroviruses, and milk pesteurization system) are presented. The advantages of using guanidine-dependent variants of enteroviruses for modeling and investigations of virological processes in the environment and potentials of the method are analysed.