Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Development of a CRISPR-Cas12a based assay for the detection of swine enteric coronaviruses in pig herds in China.
Adv Biotechnol (Singap)
February 2024
State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
Porcine epidemic diarrhea virus (PEDV), Transmissible gastroenteritis virus (TGEV), Porcine deltacoronavirus (PDCoV) and Swine acute diarrhea syndrome coronavirus (SADS-CoV) rank among the most frequently encountered swine enteric coronaviruses (SECoVs), leading to substantial economic losses to the swine industry. The availability of a rapid and highly sensitive detection method proves beneficial for the monitoring and surveillance of SECoVs. Based on the N genes of four distinct SECoVs, a novel detection method was developed in this study by combining recombinant enzyme polymerase isothermal amplification (RPA) with clustered regularly interspaced short palindromic repeats (CRISPR)-associated proteins (Cas) 12a.
View Article and Find Full Text PDFEffectiveness of rotavirus vaccine following introduction in the childhood immunization program in Northeast India.
Indian J Med Microbiol
January 2025
Department of Microbiology, RIMS, Lamphelpat, Imphal - 795004, Manipur, India. Electronic address:
Background: Rotavirus diarrhoea is a major cause of mortality and morbidity in children under five years of age. The WHO has recommended vaccination against this agent especially in countries with high mortality rates. As India accounts for almost a quarter of worldwide rotaviral diarrhoea cases, the government has introduced indigenously manufactured vaccines in the national immunization schedule which has been implemented in four phases.
View Article and Find Full Text PDFXanomeline-Trospium for Adults with Schizophrenia Experiencing Acute Psychosis: A Systematic Review and Meta-analysis of Safety and Tolerability Outcomes.
Pharmacopsychiatry
January 2025
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
The United States Food and Drug Administration approved the xanomeline-trospium combination in September 2024 for treating schizophrenia, based in part on three double-blind, randomized placebo-controlled trials in adults with schizophrenia experiencing acute psychosis. This random-effects model pairwise meta-analysis of those three trials found that xanomeline-trospium was comparable to placebo in terms of all-cause discontinuation, discontinuation rate due to adverse events, Simpson-Angus Scale score change, Barnes Akathisia Rating Scale score change, body weight change, body mass index change, blood pressure change, serum total cholesterol change, blood glucose change, QTc interval changes, and the incidence of headache, somnolence, insomnia, dizziness, akathisia, agitation, tachycardia, gastroesophageal reflux disease, diarrhea, increased weight, and decreased appetite. However, xanomeline-trospium was associated with a higher incidence of at least one adverse event, dry mouth, hypertension, nausea, vomiting, dyspepsia, and constipation, and increased serum triglyceride compared with placebo.
View Article and Find Full Text PDF[Investigation of Virulence Genes in Campylobacter Species Isolated from Patients with Acute Diarrhea].
Mikrobiyol Bul
January 2025
Selçuk Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Konya.
Akut gastroenterit dünya genelinde en yaygın enfeksiyon hastalıklarından biridir. Bu hastalıklar gelişmekte olan ülkelerde çocuk ölümlerine ve ciddi ekonomik kayıplara neden olmuştur. Hastalık genellikle yaygın diyare şeklinde kendini gösterse de bazı olgularda şiddetli enfeksiyon belirtilerine, hatta ölümlere neden olmuştur.
View Article and Find Full Text PDFBeyond the Atypical: Gastrointestinal Manifestations in Kawasaki Disease.
Cureus
December 2024
General Pediatrics, Al Qassimi Women's and Children's Hospital, Sharjah, ARE.
Kawasaki disease (KD) is an acute vasculitis mainly seen in children, with a specific risk for coronary artery involvement. Atypical symptoms can sometimes result in missed diagnoses, delaying necessary treatment and increasing the chances of serious cardiovascular complications. We report a case of a six-month-old previously healthy girl who had not been vaccinated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!