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Learning Curve of Microsurgical Anastomosis: Training for Resident Education.
J Am Acad Orthop Surg
January 2025
From the Department of Orthopaedic Surgery, Dankook University Hospital, Dankook University College of Medicine, Cheonan, South Korea.
Background: Acquiring microsurgical anastomosis skills requires considerable time and effort. Moreover, appropriate and systematic training for acquiring microsurgical anastomosis skills is lacking. Therefore, this study investigated the learning curve for acquiring microsurgical anastomosis techniques among orthopaedic surgery residents.
View Article and Find Full Text PDFNon-Invasive Prenatal Diagnosis of Chromosomal and Monogenic Disease by a Novel Bioinspired Micro-Nanochip for Isolating Fetal Nucleated Red Blood Cells.
Int J Nanomedicine
December 2024
Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, People's Republic of China.
Purpose: Fetal nucleated red blood cells (fNRBCs) in the peripheral blood of pregnant women contain comprehensive fetal genetic information, making them an ideal target for non-invasive prenatal diagnosis (NIPD). However, challenges in identifying, enriching, and detecting fNRBCs limit their diagnostic potential.
Methods: To overcome these obstacles, we developed a novel biomimetic chip, replicating the micro-nano structure of red rose petals on polydimethylsiloxane (PDMS).
Nanogrooved Elastomeric Diaphragm Arrays for Assessment of Cardiomyocytes under Synergistic Effects of Circular Mechanical Stimuli and Electrical Conductivity to Enhance Intercellular Communication.
ACS Biomater Sci Eng
January 2025
Electrical and Computer Engineering, University of Virginia, Charlottesville, Virginia 22904, United States.
Cardiovascular diseases remain the leading cause of mortality, necessitating advancements in cardiac tissue engineering platforms for improved disease modeling, drug screening, and regenerative therapies. The chief challenge to recapitulating the beating behavior of cardiomyocytes is creation of the circular stress profile experienced by hollow organs in the natural heart due to filling pressure and integrated strategies for intercellular communication to promote cell-to-cell connections. We present a platform featuring addressable arrays of nanogrooved polydimethylsiloxane (PDMS) diaphragms for cell alignment and circular mechanical stimulation, with embedded silver nanowires (AgNWs) for electrical cues, so that cardiomyocyte functionality can be assessed under these synergistic influences.
View Article and Find Full Text PDFPreparation and Antibacterial Properties of Poly (l-Lactic Acid)-Oriented Microporous Materials.
Biomolecules
November 2024
CCTEG Coal Mining Research Institute, Beijing 101399, China.
In this manuscript, an efficient self-reinforcing technology-solid hot drawing (SHD) technology-was combined with green processing supercritical carbon dioxide (SC-CO) foaming technology to promote poly (l-lactic acid) (PLLA) to form an oriented micropore structure. In addition, Polydimethylsiloxane (PDMS), with a high affinity of CO and biological safety, was introduced to enhance the nucleation effect in SC-CO foaming and co-regulate the uniformity of oriented micropores' structure. The results showed that orientation induced PLLA crystallization, so the tensile strength was improved; the maximum tensile strength of the oriented micropores' PLLA reached 151.
View Article and Find Full Text PDFAssociation between metabolic and bariatric surgery and malignancy: a systematic review, meta-analysis, trends, and conclusions.
Surg Obes Relat Dis
October 2024
Department of Surgery A, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel; The Department of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Electronic address:
Background: Conflicting studies have investigated the association between obesity, metabolic and bariatric surgery (MBS), and cancer.
Objectives: Our study aimed at elucidating the trends in cancer incidence that are related to obesity and weight loss managed through MBSs, like Colo-rectal, breast, uterine, and esophageal cancer.
Setting: We conducted a search using PubMed, Embase, and the Cochrane Library electronic databases through May 2020.
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