The involvement of light (L) and dense (D) bovine rotavirus particle types during virus replication has been studied. It was found that infectious parental L virions are uncoated in vivo to a particle similar to native D particles. Differences in the rate of synthesis and relative yields of L and D particles in MDBK and MA-104 cells have been detected. Results from pulse-chase labeling experiments indicate that D particles serve as morphogenic precursors to the complete L virion.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC288694 | PMC |
| http://dx.doi.org/10.1128/JVI.34.1.272-276.1980 | DOI Listing |
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