A double-blind comparative study to estimate the effects of tiapride when compared to placebo was conducted in 29 patients with pain from cancer. Each patient acted for his own control. Excellent or good results were obtained in 14 cases with tiapride against 6 with placebo, and moderate or no results in 15 patients on tiapride and 23 on placebo. There is a highly significant statistical difference in favour of tiapride for efficacy, but no significant difference was noted between tolerance of tiapride and placebo.
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