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[Fatal poisoning in Mali].

Med Sante Trop

April 2015

Laboratoire de génétique et biométrie, faculté des sciences, université Ibn Tofail, Kénitra, Maroc.

Aims: The aim of this study was to determine the epidemiological characteristics of the cases of fatal poisoning in Mali.

Methods: This retrospective study examined the cases of fatal poisoning recorded between 2000 and 2010 in six Health Reference centers, six regional hospitals and three university hospitals in the district of Bamako.

Results: During the study period, 146 cases of fatal poisoning were recorded, accounting for 4.

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The authors reported histological characteristics (on post-mortem examination) of 12 cases of lethal acute colchicine intoxication and compare these results with the 5 previous anatomical studies of such cases in the literature. Abnormal mitosis (stathmocinesis, "caryomerie", caryorrhexis and mitonecrosis) are constant and essentially seen in the bone marrow and digestive mucosae, especially in oesophagus which squamous epithelium is more resistant to autolysis than others digestive mucosae. Biological or histological symptoms or lesions of intravascular diffuse coagulation are present 7 cases but both biological and histological manifestations in only one case.

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